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Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells
Herpes simplex virus type 1 (HSV-1) is a common virus of mankind and HSV-1 infections are a significant cause of blindness. The current antiviral treatment of herpes infection relies on acyclovir and related compounds. However, acyclovir resistance emerges especially in the long term prophylactic tr...
Autores principales: | Kalke, Kiira, Lund, Liisa M., Nyman, Marie C., Levanova, Alesia A., Urtti, Arto, Poranen, Minna M., Hukkanen, Veijo, Paavilainen, Henrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292126/ https://www.ncbi.nlm.nih.gov/pubmed/35793357 http://dx.doi.org/10.1371/journal.ppat.1010688 |
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