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Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells

Herpes simplex virus type 1 (HSV-1) is a common virus of mankind and HSV-1 infections are a significant cause of blindness. The current antiviral treatment of herpes infection relies on acyclovir and related compounds. However, acyclovir resistance emerges especially in the long term prophylactic tr...

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Detalles Bibliográficos
Autores principales: Kalke, Kiira, Lund, Liisa M., Nyman, Marie C., Levanova, Alesia A., Urtti, Arto, Poranen, Minna M., Hukkanen, Veijo, Paavilainen, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292126/
https://www.ncbi.nlm.nih.gov/pubmed/35793357
http://dx.doi.org/10.1371/journal.ppat.1010688

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