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Functional non‐coding RNAs in vascular diseases

Recently, advances in genomic technology such as RNA sequencing and genome‐wide profiling have enabled the identification of considerable numbers of non‐coding RNAs (ncRNAs). MicroRNAs have been studied for decades, leading to the identification of those with disease‐causing and/or protective effect...

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Autores principales: Ono, Koh, Horie, Takahiro, Baba, Osamu, Kimura, Masahiro, Tsuji, Shuhei, Rodriguez, Randolph Ruiz, Miyagawa, Sawa, Kimura, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292203/
https://www.ncbi.nlm.nih.gov/pubmed/33340430
http://dx.doi.org/10.1111/febs.15678
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author Ono, Koh
Horie, Takahiro
Baba, Osamu
Kimura, Masahiro
Tsuji, Shuhei
Rodriguez, Randolph Ruiz
Miyagawa, Sawa
Kimura, Takeshi
author_facet Ono, Koh
Horie, Takahiro
Baba, Osamu
Kimura, Masahiro
Tsuji, Shuhei
Rodriguez, Randolph Ruiz
Miyagawa, Sawa
Kimura, Takeshi
author_sort Ono, Koh
collection PubMed
description Recently, advances in genomic technology such as RNA sequencing and genome‐wide profiling have enabled the identification of considerable numbers of non‐coding RNAs (ncRNAs). MicroRNAs have been studied for decades, leading to the identification of those with disease‐causing and/or protective effects in vascular disease. Although other ncRNAs such as long ncRNAs have not been fully described yet, recent studies have indicated their important functions in the development of vascular diseases. Here, we summarize the current understanding of the mechanisms and functions of ncRNAs, focusing on microRNAs, circular RNAs and long ncRNAs in vascular diseases.
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spelling pubmed-92922032022-07-20 Functional non‐coding RNAs in vascular diseases Ono, Koh Horie, Takahiro Baba, Osamu Kimura, Masahiro Tsuji, Shuhei Rodriguez, Randolph Ruiz Miyagawa, Sawa Kimura, Takeshi FEBS J State‐of‐the‐Art Reviews Recently, advances in genomic technology such as RNA sequencing and genome‐wide profiling have enabled the identification of considerable numbers of non‐coding RNAs (ncRNAs). MicroRNAs have been studied for decades, leading to the identification of those with disease‐causing and/or protective effects in vascular disease. Although other ncRNAs such as long ncRNAs have not been fully described yet, recent studies have indicated their important functions in the development of vascular diseases. Here, we summarize the current understanding of the mechanisms and functions of ncRNAs, focusing on microRNAs, circular RNAs and long ncRNAs in vascular diseases. John Wiley and Sons Inc. 2021-01-07 2021-11 /pmc/articles/PMC9292203/ /pubmed/33340430 http://dx.doi.org/10.1111/febs.15678 Text en © 2020 The Authors. The FEBS Journal published by John Wiley &  Sons Ltd on behalf of Federation of European Biochemical Societies. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle State‐of‐the‐Art Reviews
Ono, Koh
Horie, Takahiro
Baba, Osamu
Kimura, Masahiro
Tsuji, Shuhei
Rodriguez, Randolph Ruiz
Miyagawa, Sawa
Kimura, Takeshi
Functional non‐coding RNAs in vascular diseases
title Functional non‐coding RNAs in vascular diseases
title_full Functional non‐coding RNAs in vascular diseases
title_fullStr Functional non‐coding RNAs in vascular diseases
title_full_unstemmed Functional non‐coding RNAs in vascular diseases
title_short Functional non‐coding RNAs in vascular diseases
title_sort functional non‐coding rnas in vascular diseases
topic State‐of‐the‐Art Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292203/
https://www.ncbi.nlm.nih.gov/pubmed/33340430
http://dx.doi.org/10.1111/febs.15678
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