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Functional non‐coding RNAs in vascular diseases
Recently, advances in genomic technology such as RNA sequencing and genome‐wide profiling have enabled the identification of considerable numbers of non‐coding RNAs (ncRNAs). MicroRNAs have been studied for decades, leading to the identification of those with disease‐causing and/or protective effect...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292203/ https://www.ncbi.nlm.nih.gov/pubmed/33340430 http://dx.doi.org/10.1111/febs.15678 |
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author | Ono, Koh Horie, Takahiro Baba, Osamu Kimura, Masahiro Tsuji, Shuhei Rodriguez, Randolph Ruiz Miyagawa, Sawa Kimura, Takeshi |
author_facet | Ono, Koh Horie, Takahiro Baba, Osamu Kimura, Masahiro Tsuji, Shuhei Rodriguez, Randolph Ruiz Miyagawa, Sawa Kimura, Takeshi |
author_sort | Ono, Koh |
collection | PubMed |
description | Recently, advances in genomic technology such as RNA sequencing and genome‐wide profiling have enabled the identification of considerable numbers of non‐coding RNAs (ncRNAs). MicroRNAs have been studied for decades, leading to the identification of those with disease‐causing and/or protective effects in vascular disease. Although other ncRNAs such as long ncRNAs have not been fully described yet, recent studies have indicated their important functions in the development of vascular diseases. Here, we summarize the current understanding of the mechanisms and functions of ncRNAs, focusing on microRNAs, circular RNAs and long ncRNAs in vascular diseases. |
format | Online Article Text |
id | pubmed-9292203 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92922032022-07-20 Functional non‐coding RNAs in vascular diseases Ono, Koh Horie, Takahiro Baba, Osamu Kimura, Masahiro Tsuji, Shuhei Rodriguez, Randolph Ruiz Miyagawa, Sawa Kimura, Takeshi FEBS J State‐of‐the‐Art Reviews Recently, advances in genomic technology such as RNA sequencing and genome‐wide profiling have enabled the identification of considerable numbers of non‐coding RNAs (ncRNAs). MicroRNAs have been studied for decades, leading to the identification of those with disease‐causing and/or protective effects in vascular disease. Although other ncRNAs such as long ncRNAs have not been fully described yet, recent studies have indicated their important functions in the development of vascular diseases. Here, we summarize the current understanding of the mechanisms and functions of ncRNAs, focusing on microRNAs, circular RNAs and long ncRNAs in vascular diseases. John Wiley and Sons Inc. 2021-01-07 2021-11 /pmc/articles/PMC9292203/ /pubmed/33340430 http://dx.doi.org/10.1111/febs.15678 Text en © 2020 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | State‐of‐the‐Art Reviews Ono, Koh Horie, Takahiro Baba, Osamu Kimura, Masahiro Tsuji, Shuhei Rodriguez, Randolph Ruiz Miyagawa, Sawa Kimura, Takeshi Functional non‐coding RNAs in vascular diseases |
title | Functional non‐coding RNAs in vascular diseases |
title_full | Functional non‐coding RNAs in vascular diseases |
title_fullStr | Functional non‐coding RNAs in vascular diseases |
title_full_unstemmed | Functional non‐coding RNAs in vascular diseases |
title_short | Functional non‐coding RNAs in vascular diseases |
title_sort | functional non‐coding rnas in vascular diseases |
topic | State‐of‐the‐Art Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292203/ https://www.ncbi.nlm.nih.gov/pubmed/33340430 http://dx.doi.org/10.1111/febs.15678 |
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