Iron distribution in different tissues of homozygous Mask (msk/msk) mice and the effects of oral iron treatments

Iron‐refractory iron deficiency anemia (IRIDA) is an autosomal recessive disorder caused by genetic mutations on TMPRSS6 gene which encodes Matriptase2 (MT2). An altered MT2 cannot appropriately suppress hepatic BMP6/SMAD signaling in case of low iron, hence hepcidin excess blocks dietary iron absor...

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Detalles Bibliográficos
Autores principales: Asperti, Michela, Brilli, Elisa, Denardo, Andrea, Gryzik, Magdalena, Pagani, Francesca, Busti, Fabiana, Tarantino, Germano, Arosio, Paolo, Girelli, Domenico, Poli, Maura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292262/
https://www.ncbi.nlm.nih.gov/pubmed/34343368
http://dx.doi.org/10.1002/ajh.26311

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