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Randomized, Double‐Blind, Controlled Study to Evaluate Safety and Pharmacokinetics of Single Ascending Doses of ASP5354, an Investigational Imaging Product, in Healthy Adult Volunteers

Intraoperative ureter identification helps reduce the risk of ureteral injury. Currently, no suitable agents for real‐time ureter visualization are approved. ASP5354 (TK‐1) is a novel indocyanine green derivative. In this first‐in‐human phase 1, double‐blind, sequential ascending‐dose study, urethra...

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Detalles Bibliográficos
Autores principales:	Murase, Tosei, Takizawa, Masaomi, Galitz, Lawrence, Flach, Stephen, Murray, Valene, Gufford, Brandon, Suwa, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292347/ https://www.ncbi.nlm.nih.gov/pubmed/34427049 http://dx.doi.org/10.1002/cpdd.1013

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