Cargando…
Zfhx3 modulates retinal sensitivity and circadian responses to light
Mutations in transcription factors often exhibit pleiotropic effects related to their complex expression patterns and multiple regulatory targets. One such mutation in the zinc finger homeobox 3 (ZFHX3) transcription factor, short circuit (Sci, Zfhx3(Sci/+) ), is associated with significant circadia...
Autores principales: | Hughes, Steven, Edwards, Jessica K., Wilcox, Ashleigh G., Pothecary, Carina A., Barnard, Alun R., Joynson, Russell, Joynson, Greg, Hankins, Mark W., Peirson, Stuart N., Banks, Gareth, Nolan, Patrick M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292409/ https://www.ncbi.nlm.nih.gov/pubmed/34383984 http://dx.doi.org/10.1096/fj.202100563R |
Ejemplares similares
-
Zfhx3-mediated genetic ablation of the SCN abolishes light entrainable circadian activity while sparing food anticipatory activity
por: Wilcox, Ashleigh G., et al.
Publicado: (2021) -
The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis
por: Parsons, Michael J., et al.
Publicado: (2015) -
Inducible Knockout of Mouse Zfhx3 Emphasizes Its Key Role in Setting the Pace and Amplitude of the Adult Circadian Clock
por: Wilcox, Ashleigh G., et al.
Publicado: (2017) -
Differential roles for cryptochromes in the mammalian retinal clock
por: Wong, Jovi C. Y., et al.
Publicado: (2018) -
Attenuated pupillary light responses and downregulation of opsin expression parallel decline in circadian disruption in two different mouse models of Huntington’s disease
por: Ouk, Koliane, et al.
Publicado: (2016)