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TLR22-Induced Pro-Apoptotic mtROS Abets UPR(mt)-Mediated Mitochondrial Fission in Aeromonas hydrophila-Infected Headkidney Macrophages of Clarias gariepinus

Toll-like receptors (TLRs) are epitomized as the first line of defense against pathogens. Amongst TLRs, TLR22 is expressed in non-mammalian aquatic vertebrates, including fish. Using headkidney macrophages (HKM) of Clarias gariepinus, we reported the pro-apoptotic and microbicidal role of TLR22 in A...

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Detalles Bibliográficos
Autores principales:	Kumar, Manmohan, Sharma, Shagun, Haque, Munira, Kumar, Jai, Hathi, Umesh Prasad Sah, Mazumder, Shibnath
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292580/ https://www.ncbi.nlm.nih.gov/pubmed/35860264 http://dx.doi.org/10.3389/fimmu.2022.931021

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