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Neuromuscular Electrical Stimulation Reduces Leg Cramps in Patients With Lumbar Degenerative Disorders: A Randomized Placebo‐Controlled Trial

OBJECTIVES: Lumbar spinal stenosis (LSS) and lumbar disc herniation (LDH) are often accompanied by frequently occurring leg cramps severely affecting patients' life and sleep quality. Recent evidence suggests that neuromuscular electric stimulation (NMES) of cramp‐prone muscles may prevent cram...

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Autores principales: Harmsen, Jan‐Frieder, Sistig, Anna, Fasse, Alessandro, Hackl, Michael, Wegmann, Kilian, Behringer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292613/
https://www.ncbi.nlm.nih.gov/pubmed/33169444
http://dx.doi.org/10.1111/ner.13315
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author Harmsen, Jan‐Frieder
Sistig, Anna
Fasse, Alessandro
Hackl, Michael
Wegmann, Kilian
Behringer, Michael
author_facet Harmsen, Jan‐Frieder
Sistig, Anna
Fasse, Alessandro
Hackl, Michael
Wegmann, Kilian
Behringer, Michael
author_sort Harmsen, Jan‐Frieder
collection PubMed
description OBJECTIVES: Lumbar spinal stenosis (LSS) and lumbar disc herniation (LDH) are often accompanied by frequently occurring leg cramps severely affecting patients' life and sleep quality. Recent evidence suggests that neuromuscular electric stimulation (NMES) of cramp‐prone muscles may prevent cramps in lumbar disorders. MATERIALS AND METHODS: Thirty‐two men and women (63 ± 9 years) with LSS and/or LDH suffering from cramps were randomly allocated to four different groups. Unilateral stimulation of the gastrocnemius was applied twice a week over four weeks (3 × 6 × 5 sec stimulation trains at 30 Hz above the individual cramp threshold frequency [CTF]). Three groups received either 85%, 55%, or 25% of their maximum tolerated stimulation intensity, whereas one group only received pseudo‐stimulation. RESULTS: The number of reported leg cramps decreased in the 25% (25 ± 14 to 7 ± 4; p = 0.002), 55% (24 ± 10 to 10 ± 11; p = 0.014) and 85%NMES (23 ± 17 to 1 ± 1; p < 0.001) group, whereas it remained unchanged after pseudo‐stimulation (20 ± 32 to 19 ± 33; p > 0.999). In the 25% and 85%NMES group, this improvement was accompanied by an increased CTF (p < 0.001). CONCLUSION: Regularly applied NMES of the calf muscles reduces leg cramps in patients with LSS/LDH even at low stimulation intensity.
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spelling pubmed-92926132022-07-20 Neuromuscular Electrical Stimulation Reduces Leg Cramps in Patients With Lumbar Degenerative Disorders: A Randomized Placebo‐Controlled Trial Harmsen, Jan‐Frieder Sistig, Anna Fasse, Alessandro Hackl, Michael Wegmann, Kilian Behringer, Michael Neuromodulation MISCELLANEOUS NEUROMODULATION OBJECTIVES: Lumbar spinal stenosis (LSS) and lumbar disc herniation (LDH) are often accompanied by frequently occurring leg cramps severely affecting patients' life and sleep quality. Recent evidence suggests that neuromuscular electric stimulation (NMES) of cramp‐prone muscles may prevent cramps in lumbar disorders. MATERIALS AND METHODS: Thirty‐two men and women (63 ± 9 years) with LSS and/or LDH suffering from cramps were randomly allocated to four different groups. Unilateral stimulation of the gastrocnemius was applied twice a week over four weeks (3 × 6 × 5 sec stimulation trains at 30 Hz above the individual cramp threshold frequency [CTF]). Three groups received either 85%, 55%, or 25% of their maximum tolerated stimulation intensity, whereas one group only received pseudo‐stimulation. RESULTS: The number of reported leg cramps decreased in the 25% (25 ± 14 to 7 ± 4; p = 0.002), 55% (24 ± 10 to 10 ± 11; p = 0.014) and 85%NMES (23 ± 17 to 1 ± 1; p < 0.001) group, whereas it remained unchanged after pseudo‐stimulation (20 ± 32 to 19 ± 33; p > 0.999). In the 25% and 85%NMES group, this improvement was accompanied by an increased CTF (p < 0.001). CONCLUSION: Regularly applied NMES of the calf muscles reduces leg cramps in patients with LSS/LDH even at low stimulation intensity. John Wiley & Sons, Inc. 2020-11-09 2021-12 /pmc/articles/PMC9292613/ /pubmed/33169444 http://dx.doi.org/10.1111/ner.13315 Text en © 2020 The Authors. Neuromodulation: Technology at the Neural Interface published by Wiley Periodicals LLC on behalf of International Neuromodulation Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle MISCELLANEOUS NEUROMODULATION
Harmsen, Jan‐Frieder
Sistig, Anna
Fasse, Alessandro
Hackl, Michael
Wegmann, Kilian
Behringer, Michael
Neuromuscular Electrical Stimulation Reduces Leg Cramps in Patients With Lumbar Degenerative Disorders: A Randomized Placebo‐Controlled Trial
title Neuromuscular Electrical Stimulation Reduces Leg Cramps in Patients With Lumbar Degenerative Disorders: A Randomized Placebo‐Controlled Trial
title_full Neuromuscular Electrical Stimulation Reduces Leg Cramps in Patients With Lumbar Degenerative Disorders: A Randomized Placebo‐Controlled Trial
title_fullStr Neuromuscular Electrical Stimulation Reduces Leg Cramps in Patients With Lumbar Degenerative Disorders: A Randomized Placebo‐Controlled Trial
title_full_unstemmed Neuromuscular Electrical Stimulation Reduces Leg Cramps in Patients With Lumbar Degenerative Disorders: A Randomized Placebo‐Controlled Trial
title_short Neuromuscular Electrical Stimulation Reduces Leg Cramps in Patients With Lumbar Degenerative Disorders: A Randomized Placebo‐Controlled Trial
title_sort neuromuscular electrical stimulation reduces leg cramps in patients with lumbar degenerative disorders: a randomized placebo‐controlled trial
topic MISCELLANEOUS NEUROMODULATION
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292613/
https://www.ncbi.nlm.nih.gov/pubmed/33169444
http://dx.doi.org/10.1111/ner.13315
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