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Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney

BACKGROUND AND PURPOSE: Generation of cGMP via NO‐sensitive soluble guanylyl cyclase (sGC) has been implicated in the regulation of renal functions. Chronic kidney disease (CKD) is associated with decreased NO bioavailability, increased oxidative stress and oxidation of sGC to its haem‐free form, ap...

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Detalles Bibliográficos
Autores principales:	Stehle, Daniel, Xu, Min Ze, Schomber, Tibor, Hahn, Michael G., Schweda, Frank, Feil, Susanne, Kraehling, Jan R., Eitner, Frank, Patzak, Andreas, Sandner, Peter, Feil, Robert, Bénardeau, Agnès
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Cgmp Signalling in Cell Growth and Survival ‐ Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292672/ https://www.ncbi.nlm.nih.gov/pubmed/34096053 http://dx.doi.org/10.1111/bph.15586

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