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Abacavir pharmacokinetics in African children living with HIV: A pooled analysis describing the effects of age, malnutrition and common concomitant medications

AIMS: Abacavir is part of WHO‐recommended regimens to treat HIV in children under 15 years of age. In a pooled analysis across four studies, we describe abacavir population pharmacokinetics to investigate the influence of age, concomitant medications, malnutrition and formulation. METHODS: A total o...

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Detalles Bibliográficos
Autores principales: Tikiso, Tjokosela, McIlleron, Helen, Burger, David, Gibb, Diana, Rabie, Helena, Lee, Janice, Lallemant, Marc, Cotton, Mark F., Archary, Moherndran, Hennig, Stefanie, Denti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292832/
https://www.ncbi.nlm.nih.gov/pubmed/34260082
http://dx.doi.org/10.1111/bcp.14984