Cargando…

Deep learning‐based model for diagnosing Alzheimer's disease and tauopathies

AIMS: This study aimed to develop a deep learning‐based model for differentiating tauopathies, including Alzheimer's disease (AD), progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and Pick's disease (PiD), based on tau‐immunostained digital slide images. METHODS: We tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koga, Shunsuke, Ikeda, Akihiro, Dickson, Dennis W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293025/ https://www.ncbi.nlm.nih.gov/pubmed/34402107 http://dx.doi.org/10.1111/nan.12759

Ejemplares similares

Globular glial tauopathy presenting clinically as atypical parkinsonism with dementia: A clinicopathological case report
por: Hoag, Thomas, et al.
Publicado: (2023)

Machine learning‐based decision tree classifier for the diagnosis of progressive supranuclear palsy and corticobasal degeneration
por: Koga, Shunsuke, et al.
Publicado: (2021)

Effects of Deferasirox in Alzheimer’s Disease and Tauopathy Animal Models
por: Kwan, Ping, et al.
Publicado: (2022)

Untangling the Tauopathy for Alzheimer’s disease and parkinsonism
por: Chang, Hui-Yun, et al.
Publicado: (2018)

Cellular and pathological heterogeneity of primary tauopathies
por: Chung, Dah-eun Chloe, et al.
Publicado: (2021)

TDP-43 Pathology in Alzheimer’s Disease
por: Meneses, Axel, et al.
Publicado: (2021)

Phosphorylated Tau in Alzheimer’s Disease and Other Tauopathies
por: Rawat, Priyanka, et al.
Publicado: (2022)

A Rapid Gene Delivery–Based Mouse Model for Early-Stage Alzheimer Disease–Type Tauopathy
por: Siman, Robert, et al.
Publicado: (2013)

Early Cognitive and Behavioral Deficits in Mouse Models for Tauopathy and Alzheimer’s Disease
por: Samaey, Celine, et al.
Publicado: (2019)

Clinical diagnoses among individuals with primary age-related tauopathy versus Alzheimer’s neuropathology
por: Teylan, Merilee, et al.
Publicado: (2019)

Deep learning reveals disease-specific signatures of white matter pathology in tauopathies
por: Vega, Anthony R., et al.
Publicado: (2021)

PET Imaging of Tau Pathology in Alzheimer’s Disease and Tauopathies
por: James, Olga G., et al.
Publicado: (2015)

Prospects for strain-specific immunotherapy in Alzheimer’s disease and tauopathies
por: Bittar, Alice, et al.
Publicado: (2018)

Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?
por: Laurent, Cyril, et al.
Publicado: (2018)

Type-I Interferons in Alzheimer's Disease and Other Tauopathies
por: Sanford, Sophie A. I., et al.
Publicado: (2022)

Clinicopathologic assessment and imaging of tauopathies in neurodegenerative dementias
por: Murray, Melissa E, et al.
Publicado: (2014)

Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer’s Disease and Related Tauopathies
por: Castillo-Carranza, Diana L, et al.
Publicado: (2017)

Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: Implications for Alzheimer disease pathogenesis
por: Terron, Heather M., et al.
Publicado: (2023)

Simple model systems reveal conserved mechanisms of Alzheimer’s disease and related tauopathies
por: Jiang, Yuwei, et al.
Publicado: (2023)

Altered localization of nucleoporin 98 in primary tauopathies
por: Dickson, John R, et al.
Publicado: (2022)

Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy
por: Clippinger, Amy K., et al.
Publicado: (2013)

LRRK2 phosphorylates novel tau epitopes and promotes tauopathy
por: Bailey, Rachel M., et al.
Publicado: (2013)

DNA Methylation in Genetic and Sporadic Forms of Neurodegeneration: Lessons from Alzheimer’s, Related Tauopathies and Genetic Tauopathies
por: Zimmer-Bensch, Geraldine, et al.
Publicado: (2021)

Assessing THK523 selectivity for tau deposits in Alzheimer’s disease and non–Alzheimer’s disease tauopathies
por: Fodero-Tavoletti, Michelle T, et al.
Publicado: (2014)

Drosophila Models of Tauopathies: What Have We Learned?
por: Gistelinck, Marc, et al.
Publicado: (2012)

Case report: Non-Alzheimer's disease tauopathy with logopenic variant primary progressive aphasia diagnosed using amyloid and tau PET
por: Momota, Yuki, et al.
Publicado: (2022)

Tau Protein Interaction Partners and Their Roles in Alzheimer’s Disease and Other Tauopathies
por: Sinsky, Jakub, et al.
Publicado: (2021)

Ion Channel Formation by Tau Protein: Implications for Alzheimer’s Disease and Tauopathies
por: Patel, Nirav, et al.
Publicado: (2015)

Cognitive Decline in Preclinical Alzheimer’s Disease: Amyloid-Beta versus Tauopathy
por: Huber, Colin M., et al.
Publicado: (2017)

Striatal amyloid is associated with tauopathy and memory decline in familial Alzheimer’s disease
por: Hanseeuw, Bernard J., et al.
Publicado: (2019)

Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model
por: Bailey, Rachel M, et al.
Publicado: (2014)

A novel deep learning approach for diagnosing Alzheimer's disease based on eye-tracking data
por: Sun, Jinglin, et al.
Publicado: (2022)

Comparative analysis of autophagy and tauopathy related markers in cerebral ischemia and Alzheimer’s disease animal models
por: Villamil-Ortiz, Javier G., et al.
Publicado: (2015)

APOE ε2 is associated with increased tau pathology in primary tauopathy
por: Zhao, Na, et al.
Publicado: (2018)

Mixed Alzheimer's and Lewy-related Pathology Can Cause Corticobasal Syndrome with Visual Hallucinations
por: Kasanuki, Koji, et al.
Publicado: (2019)

Associations of Alzheimer’s disease risk variants with gene expression, amyloidosis, tauopathy, and neurodegeneration
por: Tan, Meng-Shan, et al.
Publicado: (2021)

Tau-focused therapy and tau transmission: Implications for Alzheimer’s Disease and related tauopathies
por: Trojanowski, John Q
Publicado: (2013)

The Link Between Tau and Insulin Signaling: Implications for Alzheimer’s Disease and Other Tauopathies
por: Gonçalves, Rafaella Araujo, et al.
Publicado: (2019)

Amyloid and Tau Positron Emission Tomography Imaging in Alzheimer’s Disease and Other Tauopathies
por: Maschio, Cinzia, et al.
Publicado: (2022)

Neuroimmune proteins can differentiate between tauopathies
por: Cherry, Jonathan D., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9go7elgp3uha6qsd3v85a7qktv