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Assessment of pharyngeal motor function using a novel velopharyngeal squeeze maneuver and a novel endoscopic pharyngeal contraction grade scale in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma

BACKGROUND: To investigate a novel velopharyngeal squeeze maneuver (VPSM) and novel endoscopic pharyngeal contraction grade (EPCG) scale for the evaluation of pharyngeal motor function. METHODS: During endoscopic examination of 77 post‐irradiated nasopharyngeal carcinoma patients and control subject...

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Autores principales: Ku, Peter K. M., Vlantis, Alexander C., Hui, Thomas S. C., Yeung, David C. M., Lee, Alex K. F., Law, Thomas, Chan, Simon Y. P., Poon, Esther S. M., Lee, Sophie Y. Y., Chan, Becky Y. T., Cheung, Twinky Y. L., Lok, Laurie Y. W., Cheng, Dennis T. H., Li, Jade W. S., Yam, Ken C. W., Ho, Christina S. M., Fung, Kristy P. T., Chan, Coco S. Y., Wang, William H. S., Wong, Jeffrey K. T., Abdullah, Victor, van Hasselt, Andrew, Tong, Michael C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293071/
https://www.ncbi.nlm.nih.gov/pubmed/34523766
http://dx.doi.org/10.1002/hed.26871
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author Ku, Peter K. M.
Vlantis, Alexander C.
Hui, Thomas S. C.
Yeung, David C. M.
Lee, Alex K. F.
Law, Thomas
Chan, Simon Y. P.
Poon, Esther S. M.
Lee, Sophie Y. Y.
Chan, Becky Y. T.
Cheung, Twinky Y. L.
Lok, Laurie Y. W.
Cheng, Dennis T. H.
Li, Jade W. S.
Yam, Ken C. W.
Ho, Christina S. M.
Fung, Kristy P. T.
Chan, Coco S. Y.
Wang, William H. S.
Wong, Jeffrey K. T.
Abdullah, Victor
van Hasselt, Andrew
Tong, Michael C. F.
author_facet Ku, Peter K. M.
Vlantis, Alexander C.
Hui, Thomas S. C.
Yeung, David C. M.
Lee, Alex K. F.
Law, Thomas
Chan, Simon Y. P.
Poon, Esther S. M.
Lee, Sophie Y. Y.
Chan, Becky Y. T.
Cheung, Twinky Y. L.
Lok, Laurie Y. W.
Cheng, Dennis T. H.
Li, Jade W. S.
Yam, Ken C. W.
Ho, Christina S. M.
Fung, Kristy P. T.
Chan, Coco S. Y.
Wang, William H. S.
Wong, Jeffrey K. T.
Abdullah, Victor
van Hasselt, Andrew
Tong, Michael C. F.
author_sort Ku, Peter K. M.
collection PubMed
description BACKGROUND: To investigate a novel velopharyngeal squeeze maneuver (VPSM) and novel endoscopic pharyngeal contraction grade (EPCG) scale for the evaluation of pharyngeal motor function. METHODS: During endoscopic examination of 77 post‐irradiated nasopharyngeal carcinoma patients and control subjects, VPSM was rated and lateral pharyngeal wall movement graded with EPCG scale during swallowing. Pharyngeal constriction ratio (PCR) measured by videofluoroscopy was used for correlation. RESULTS: VPSM and EPCG scale showed almost perfect intra‐rater and inter‐rater reliability (Kappa: >0.90). VPSM was present in 61% of patients suggesting good pharyngeal motor function. VPSM was predictive of EPCG scale (Wald statistic = 29.99, p < 0.001). EPCG scale also correlated strongly with PCR (r: 0.812) and was predictive for aspiration (odds ratio: 22.14 [95% CI 5.01–97.89, p < 0.001]). CONCLUSIONS: VPSM and EPCG scale are two novel tools to assess pharyngeal motor function, and both correlate well with pharyngeal contractility and aspiration.
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spelling pubmed-92930712022-07-20 Assessment of pharyngeal motor function using a novel velopharyngeal squeeze maneuver and a novel endoscopic pharyngeal contraction grade scale in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma Ku, Peter K. M. Vlantis, Alexander C. Hui, Thomas S. C. Yeung, David C. M. Lee, Alex K. F. Law, Thomas Chan, Simon Y. P. Poon, Esther S. M. Lee, Sophie Y. Y. Chan, Becky Y. T. Cheung, Twinky Y. L. Lok, Laurie Y. W. Cheng, Dennis T. H. Li, Jade W. S. Yam, Ken C. W. Ho, Christina S. M. Fung, Kristy P. T. Chan, Coco S. Y. Wang, William H. S. Wong, Jeffrey K. T. Abdullah, Victor van Hasselt, Andrew Tong, Michael C. F. Head Neck Original Articles BACKGROUND: To investigate a novel velopharyngeal squeeze maneuver (VPSM) and novel endoscopic pharyngeal contraction grade (EPCG) scale for the evaluation of pharyngeal motor function. METHODS: During endoscopic examination of 77 post‐irradiated nasopharyngeal carcinoma patients and control subjects, VPSM was rated and lateral pharyngeal wall movement graded with EPCG scale during swallowing. Pharyngeal constriction ratio (PCR) measured by videofluoroscopy was used for correlation. RESULTS: VPSM and EPCG scale showed almost perfect intra‐rater and inter‐rater reliability (Kappa: >0.90). VPSM was present in 61% of patients suggesting good pharyngeal motor function. VPSM was predictive of EPCG scale (Wald statistic = 29.99, p < 0.001). EPCG scale also correlated strongly with PCR (r: 0.812) and was predictive for aspiration (odds ratio: 22.14 [95% CI 5.01–97.89, p < 0.001]). CONCLUSIONS: VPSM and EPCG scale are two novel tools to assess pharyngeal motor function, and both correlate well with pharyngeal contractility and aspiration. John Wiley & Sons, Inc. 2021-09-15 2021-11 /pmc/articles/PMC9293071/ /pubmed/34523766 http://dx.doi.org/10.1002/hed.26871 Text en © 2021 Ernst & Sohn Verlag für Architektur und technische Wissenschaften GmbH & Co. KG. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Ku, Peter K. M.
Vlantis, Alexander C.
Hui, Thomas S. C.
Yeung, David C. M.
Lee, Alex K. F.
Law, Thomas
Chan, Simon Y. P.
Poon, Esther S. M.
Lee, Sophie Y. Y.
Chan, Becky Y. T.
Cheung, Twinky Y. L.
Lok, Laurie Y. W.
Cheng, Dennis T. H.
Li, Jade W. S.
Yam, Ken C. W.
Ho, Christina S. M.
Fung, Kristy P. T.
Chan, Coco S. Y.
Wang, William H. S.
Wong, Jeffrey K. T.
Abdullah, Victor
van Hasselt, Andrew
Tong, Michael C. F.
Assessment of pharyngeal motor function using a novel velopharyngeal squeeze maneuver and a novel endoscopic pharyngeal contraction grade scale in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma
title Assessment of pharyngeal motor function using a novel velopharyngeal squeeze maneuver and a novel endoscopic pharyngeal contraction grade scale in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma
title_full Assessment of pharyngeal motor function using a novel velopharyngeal squeeze maneuver and a novel endoscopic pharyngeal contraction grade scale in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma
title_fullStr Assessment of pharyngeal motor function using a novel velopharyngeal squeeze maneuver and a novel endoscopic pharyngeal contraction grade scale in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma
title_full_unstemmed Assessment of pharyngeal motor function using a novel velopharyngeal squeeze maneuver and a novel endoscopic pharyngeal contraction grade scale in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma
title_short Assessment of pharyngeal motor function using a novel velopharyngeal squeeze maneuver and a novel endoscopic pharyngeal contraction grade scale in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma
title_sort assessment of pharyngeal motor function using a novel velopharyngeal squeeze maneuver and a novel endoscopic pharyngeal contraction grade scale in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293071/
https://www.ncbi.nlm.nih.gov/pubmed/34523766
http://dx.doi.org/10.1002/hed.26871
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