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Characteristics of α2,3‐sialyl N‐glycosylated PSA as a biomarker for clinically significant prostate cancer in men with elevated PSA level

BACKGROUND: The presence of glycosylated isoforms of prostate‐specific antigen (PSA) in prostate cancer (PC) cells is a potential marker of their aggressiveness. We characterized the origin of α2,3‐sialylated prostate‐specific antigen (S23PSA) by tissue‐based sialylation‐related gene expression and...

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Detalles Bibliográficos
Autores principales: Yoneyama, Tohru, Yamamoto, Hayato, Sutoh Yoneyama, Mihoko, Tobisawa, Yuki, Hatakeyama, Shingo, Narita, Takuma, Kodama, Hirotake, Momota, Masaki, Ito, Hiroyuki, Narita, Shintaro, Tsushima, Fumiyasu, Mitsuzuka, Koji, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Duivenvoorden, Wilhelmina, Pinthus, Jehonathan H., Kakeda, Shingo, Ito, Akihiro, Tsuchiya, Norihiko, Habuchi, Tomonori, Ohyama, Chikara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293073/
https://www.ncbi.nlm.nih.gov/pubmed/34549452
http://dx.doi.org/10.1002/pros.24239