Chemoenzymatic Dynamic Kinetic Asymmetric Transformations of β‐Hydroxyketones

Herein we report on the development and application of chemoenzymatic Dynamic Kinetic Asymmetric Transformation (DYKAT) of α‐substituted β‐hydroxyketones (β‐HKs), using Candida antartica lipase B (CALB) as transesterification catalyst and a ruthenium complex as epimerization catalyst. An operational...

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Detalles Bibliográficos
Autores principales: Hilker, Simon, Posevins, Daniels, Unelius, C. Rikard, Bäckvall, Jan‐E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293354/
https://www.ncbi.nlm.nih.gov/pubmed/34428339
http://dx.doi.org/10.1002/chem.202102683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293354/
https://www.ncbi.nlm.nih.gov/pubmed/34428339
http://dx.doi.org/10.1002/chem.202102683

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