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Ex vivo microRNA and gene expression profiling of human Tr1‐like cells suggests a role for miR‐92a and ‐125a in the regulation of EOMES and IL‐10R

Ex vivo gene expression and miRNA profiling of Eomes(+)Tr1‐like cells suggested that they represent a differentiation stage that is intermediate between Th1‐cells and cytotoxic CD4(+) T‐cells. Several microRNAs were downregulated in Eomes(+)Tr1‐like cells that might inhibit Tr1‐cell differentiation....

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Detalles Bibliográficos
Autores principales: De Simone, Marco, Chirichella, Michele, Emming, Stefan, Mazzara, Saveria, Ranzani, Valeria, Gruarin, Paola, Moschetti, Giorgia, Pulvirenti, Nadia, Maglie, Stefano, Vasco, Chiara, Crosti, Maria Cristina, Rossetti, Grazisa, Pagani, Massimiliano, Abrignani, Sergio, Monticelli, Silvia, Geginat, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293355/
https://www.ncbi.nlm.nih.gov/pubmed/34528258
http://dx.doi.org/10.1002/eji.202149315