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Primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with BMP‐2 and autogenous bone blocks: A 3D analysis after 3 years
OBJECTIVES: To test whether or not primary bone augmentation using xenograft blocks infused with BMP‐2 or autogenous bone blocks lead to similar results regarding the implant survival and 3D marginal soft tissue contours. METHODS: Twenty‐four patients with an insufficient ridge width for implant pla...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293361/ https://www.ncbi.nlm.nih.gov/pubmed/34543475 http://dx.doi.org/10.1111/clr.13843 |
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author | Bienz, Stefan P. Payer, Michael Hjerppe, Jenni Hüsler, Jürg Jakse, Norbert Schmidlin, Patrick R. Hämmerle, Christoph H. F. Jung, Ronald E. Thoma, Daniel S. |
author_facet | Bienz, Stefan P. Payer, Michael Hjerppe, Jenni Hüsler, Jürg Jakse, Norbert Schmidlin, Patrick R. Hämmerle, Christoph H. F. Jung, Ronald E. Thoma, Daniel S. |
author_sort | Bienz, Stefan P. |
collection | PubMed |
description | OBJECTIVES: To test whether or not primary bone augmentation using xenograft blocks infused with BMP‐2 or autogenous bone blocks lead to similar results regarding the implant survival and 3D marginal soft tissue contours. METHODS: Twenty‐four patients with an insufficient ridge width for implant placement in need of primary augmentation were randomly assigned to either a block of deproteinized bovine bone mineral infused with rhBMP‐2 (BMP) or an intraorally harvested block of autogenous bone (ABB). At 4 months, 1–4 dental implants were placed in the regenerated area. After crown insertion and at 3 years, peri‐implant tissue parameters, two‐ and three‐dimensional radiographic parameters, and soft tissue contour changes were evaluated. Explorative mixed model analyses were performed. The level of significance was set at 5%. RESULTS: At the 3‐year follow‐up, 23 patients with 40 implants were evaluated. The implant survival rate was 100% in both groups. At baseline, the marginal hard tissue levels amounted to −0.4 ± 0.8 mm (mean ± standard deviation) in the BMP group and −0.7 ± 1.0 mm in the ABB group. At 3 years, these values were −0.2 ± 0.4 mm (BMP) and −0.6 ± 1.0 mm (ABB). At baseline, the thickness of the buccal hard tissue at the level of the implant shoulder measured 1.1 ± 1.1 mm (BMP) and 1.4 ± 1.0 mm (ABB). At 3 years, it measured 0.9 ± 0.9 mm (BMP) and 0.7 ± 0.6 mm (ABB). CONCLUSIONS: The present study demonstrated excellent implant survival rates and stable marginal hard tissue levels in both augmentation groups, 3 years after crown insertion. In addition, the clinical stability of soft and hard tissues was demonstrated in both groups. |
format | Online Article Text |
id | pubmed-9293361 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92933612022-07-20 Primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with BMP‐2 and autogenous bone blocks: A 3D analysis after 3 years Bienz, Stefan P. Payer, Michael Hjerppe, Jenni Hüsler, Jürg Jakse, Norbert Schmidlin, Patrick R. Hämmerle, Christoph H. F. Jung, Ronald E. Thoma, Daniel S. Clin Oral Implants Res Original Articles OBJECTIVES: To test whether or not primary bone augmentation using xenograft blocks infused with BMP‐2 or autogenous bone blocks lead to similar results regarding the implant survival and 3D marginal soft tissue contours. METHODS: Twenty‐four patients with an insufficient ridge width for implant placement in need of primary augmentation were randomly assigned to either a block of deproteinized bovine bone mineral infused with rhBMP‐2 (BMP) or an intraorally harvested block of autogenous bone (ABB). At 4 months, 1–4 dental implants were placed in the regenerated area. After crown insertion and at 3 years, peri‐implant tissue parameters, two‐ and three‐dimensional radiographic parameters, and soft tissue contour changes were evaluated. Explorative mixed model analyses were performed. The level of significance was set at 5%. RESULTS: At the 3‐year follow‐up, 23 patients with 40 implants were evaluated. The implant survival rate was 100% in both groups. At baseline, the marginal hard tissue levels amounted to −0.4 ± 0.8 mm (mean ± standard deviation) in the BMP group and −0.7 ± 1.0 mm in the ABB group. At 3 years, these values were −0.2 ± 0.4 mm (BMP) and −0.6 ± 1.0 mm (ABB). At baseline, the thickness of the buccal hard tissue at the level of the implant shoulder measured 1.1 ± 1.1 mm (BMP) and 1.4 ± 1.0 mm (ABB). At 3 years, it measured 0.9 ± 0.9 mm (BMP) and 0.7 ± 0.6 mm (ABB). CONCLUSIONS: The present study demonstrated excellent implant survival rates and stable marginal hard tissue levels in both augmentation groups, 3 years after crown insertion. In addition, the clinical stability of soft and hard tissues was demonstrated in both groups. John Wiley and Sons Inc. 2021-09-28 2021-12 /pmc/articles/PMC9293361/ /pubmed/34543475 http://dx.doi.org/10.1111/clr.13843 Text en © 2021 The Authors. Clinical Oral Implants Research published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles Bienz, Stefan P. Payer, Michael Hjerppe, Jenni Hüsler, Jürg Jakse, Norbert Schmidlin, Patrick R. Hämmerle, Christoph H. F. Jung, Ronald E. Thoma, Daniel S. Primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with BMP‐2 and autogenous bone blocks: A 3D analysis after 3 years |
title | Primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with BMP‐2 and autogenous bone blocks: A 3D analysis after 3 years |
title_full | Primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with BMP‐2 and autogenous bone blocks: A 3D analysis after 3 years |
title_fullStr | Primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with BMP‐2 and autogenous bone blocks: A 3D analysis after 3 years |
title_full_unstemmed | Primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with BMP‐2 and autogenous bone blocks: A 3D analysis after 3 years |
title_short | Primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with BMP‐2 and autogenous bone blocks: A 3D analysis after 3 years |
title_sort | primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with bmp‐2 and autogenous bone blocks: a 3d analysis after 3 years |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293361/ https://www.ncbi.nlm.nih.gov/pubmed/34543475 http://dx.doi.org/10.1111/clr.13843 |
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