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Structural Studies Provide New Insights into the Role of Lysine Acetylation on Substrate Recognition by CARM1 and Inform the Design of Potent Peptidomimetic Inhibitors

The dynamic interplay of post‐translational modifications (PTMs) in chromatin provides a communication system for the regulation of gene expression. An increasing number of studies have highlighted the role that such crosstalk between PTMs plays in chromatin recognition. In this study, (bio)chemical...

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Detalles Bibliográficos
Autores principales: Zhang, Yurui, Marechal, Nils, van Haren, Matthijs J., Troffer‐Charlier, Nathalie, Cura, Vincent, Cavarelli, Jean, Martin, Nathaniel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293414/
https://www.ncbi.nlm.nih.gov/pubmed/34569136
http://dx.doi.org/10.1002/cbic.202100506