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Cantharidin Inhibits Proliferation of Liver Cancer by Inducing DNA Damage via KDM4A-Dependent Histone H3K36 Demethylation

OBJECTIVE: To investigate the effect of cantharidin on DNA damage in hepatocellular carcinoma cells and its possible mechanism. METHODS: Cell proliferation assay and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay were used to analyze the effects of cantharidin on...

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Detalles Bibliográficos
Autores principales: Wei, Chao, Deng, Xiangui, Gao, Shudi, Wan, Xuemei, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293552/
https://www.ncbi.nlm.nih.gov/pubmed/35860003
http://dx.doi.org/10.1155/2022/2197071