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Discovery of dipeptidyl peptidase-4 inhibitor specific biomarker in non-alcoholic fatty liver disease mouse models using modified basket trial

BACKGROUND/AIMS: We aimed to define an optimal target population and drug-specific biomarkers that may predict dipeptidyl peptidase (DPP)-4 inhibitor responses in non-alcoholic fatty liver disease (NAFLD). METHODS: An exploration study (study I) was performed using three different NAFLD models (bask...

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Detalles Bibliográficos
Autores principales: Oh, Ju Hee, Jun, Dae Won, Kim, Hye Young, Lee, Seung Min, Yoon, Eileen L., Hwang, Jungwook, Park, Jung Hwan, Lee, Hanbi, Kim, Wankyu, Kim, Hyunsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293604/
https://www.ncbi.nlm.nih.gov/pubmed/35484644
http://dx.doi.org/10.3350/cmh.2022.0019