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Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4

BACKGROUND/AIMS: Binge drinking leads to many disorders, including alcoholic hepatosteatosis, which is characterized by intrahepatic neutrophil infiltration and increases the risk of hepatocellular carcinoma (HCC). Molecular mechanisms may involve the migration of bacterial metabolites from the gut...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Zhang, Xin, Chen, Shuo, Wang, Jiazhong, Yu, Shuo, Li, Yiming, Xu, Meng, Aboubacar, Harouna, Li, Junhui, Shan, Tao, Wang, Jixin, Cao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293619/
https://www.ncbi.nlm.nih.gov/pubmed/35508957
http://dx.doi.org/10.3350/cmh.2022.0039