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PKGIα is activated by metal-dependent oxidation in vitro but not in intact cells

Type I cGMP-dependent protein kinases (PKGIs) are important components of various signaling pathways and are canonically activated by nitric oxide– and natriuretic peptide–induced cGMP generation. However, some reports have shown that PKGIα can also be activated in vitro by oxidizing agents. Using i...

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Detalles Bibliográficos
Autores principales:	Aminzai, Sahar, Hu, Tingfei, Pilz, Renate B., Casteel, Darren E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293632/ https://www.ncbi.nlm.nih.gov/pubmed/35752367 http://dx.doi.org/10.1016/j.jbc.2022.102175

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