Structural insights into the role of the WW2 domain on tandem WW–PPxY motif interactions of oxidoreductase WWOX

Class I WW domains are present in many proteins of various functions and mediate protein interactions by binding to short linear PPxY motifs. Tandem WW domains often bind peptides with multiple PPxY motifs, but the interplay of WW–peptide interactions is not always intuitive. The WW domain–containin...

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Detalles Bibliográficos
Autores principales: Rotem-Bamberger, Shahar, Fahoum, Jamal, Keinan-Adamsky, Keren, Tsaban, Tomer, Avraham, Orly, Shalev, Deborah E., Chill, Jordan H., Schueler-Furman, Ora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293652/
https://www.ncbi.nlm.nih.gov/pubmed/35716775
http://dx.doi.org/10.1016/j.jbc.2022.102145

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