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A human IgE bispecific antibody shows potent cytotoxic capacity mediated by monocytes

The generation of bispecific antibodies (bsAbs) targeting two different antigens opens a new level of specificity and, compared to mAbs, improved clinical efficacy in cancer therapy. Currently, the different strategies for development of bsAbs primarily focus on IgG isotypes. Nevertheless, in compar...

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Detalles Bibliográficos
Autores principales:	Vukovic, Natasa, Halabi, Samer, Russo-Cabrera, Joan Salvador, Blokhuis, Bart, Berraondo, Pedro, Redegeld, Frank A.M., Zaiss, Dietmar M.W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293656/ https://www.ncbi.nlm.nih.gov/pubmed/35718062 http://dx.doi.org/10.1016/j.jbc.2022.102153

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