Targeting macrophagic SHP2 for ameliorating osteoarthritis via TLR signaling

Osteoarthritis (OA), in which M1 macrophage polarization in the synovium exacerbates disease progression, is a major cause of cartilage degeneration and functional disabilities. Therapeutic strategies of OA designed to interfere with the polarization of macrophages have rarely been reported. Here, w...

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Detalles Bibliográficos
Autores principales: Sun, Ziying, Liu, Qianqian, Lv, Zhongyang, Li, Jiawei, Xu, Xingquan, Sun, Heng, Wang, Maochun, Sun, Kuoyang, Shi, Tianshu, Liu, Zizheng, Tan, Guihua, Yan, Wenqiang, Wu, Rui, Yang, Yannick Xiaofan, Ikegawa, Shiro, Jiang, Qing, Sun, Yang, Shi, Dongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293663/
https://www.ncbi.nlm.nih.gov/pubmed/35865095
http://dx.doi.org/10.1016/j.apsb.2022.02.010

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