Repurposing econazole as a pharmacological autophagy inhibitor to treat pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is characterized by the highest mortality among carcinomas. The pathogenesis of PDAC requires elevated autophagy, inhibition of which using hydroxychloroquine has shown promise. However, current realization is impeded by its suboptimal use and unpredictable to...

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Detalles Bibliográficos
Autores principales: Weng, Ningna, Qin, Siyuan, Liu, Jiayang, Huang, Xing, Jiang, Jingwen, Zhou, Li, Zhang, Zhe, Xie, Na, Wang, Kui, Jin, Ping, Luo, Maochao, Peng, Liyuan, Nice, Edouard C., Goel, Ajay, Han, Suxia, Huang, Canhua, Zhu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293665/
https://www.ncbi.nlm.nih.gov/pubmed/35865101
http://dx.doi.org/10.1016/j.apsb.2022.01.018

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