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Biological Sex As a Critical Variable in CD4(+) Effector T Cell Function in Preclinical Models of Multiple Sclerosis
SIGNIFICANCE: T cells play a pivotal role in maintaining adaptive immune responses against pathogens. However, misdirected T cell responses against self-tissues may lead to autoimmune disease. Biological sex has profound effects on T cell function and is an important determinant of disease incidence...
Autores principales: | Umair, Muhammad, Fazazi, Mohamed Reda, Rangachari, Manu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293683/ https://www.ncbi.nlm.nih.gov/pubmed/34538129 http://dx.doi.org/10.1089/ars.2021.0202 |
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