Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination

Ubiquitination has important functions in osteoarthritis (OA), yet the mechanism remains unclear. Here, we identify the regulator of G protein signaling 12 (RGS12) in macrophages, which promotes the association between ubiquitin and IκB during inflammation. We also find that RGS12 promotes the degra...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Gongsheng, Yang, Shuting, Yang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293709/
https://www.ncbi.nlm.nih.gov/pubmed/35873013
http://dx.doi.org/10.1016/j.gendis.2021.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293709/
https://www.ncbi.nlm.nih.gov/pubmed/35873013
http://dx.doi.org/10.1016/j.gendis.2021.08.005

Ejemplares similares