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Engineering prodrug nanomicelles as pyroptosis inducer for codelivery of PI3K/mTOR and CDK inhibitors to enhance antitumor immunity
Aberrant activation of oncogenic signaling pathways in tumors can promote resistance to the antitumor immune response. However, single blockade of these pathways is usually ineffective because of the complex crosstalk and feedback among oncogenic signaling pathways. The enhanced toxicity of free sma...
Autores principales: | Yang, Qichao, Ma, Xianbin, Xiao, Yao, Zhang, Tian, Yang, Leilei, Yang, Shaochen, Liang, Mengyun, Wang, Shuo, Wu, Zhizhong, Xu, Zhigang, Sun, Zhijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293721/ https://www.ncbi.nlm.nih.gov/pubmed/35865097 http://dx.doi.org/10.1016/j.apsb.2022.02.024 |
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