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Engineering prodrug nanomicelles as pyroptosis inducer for codelivery of PI3K/mTOR and CDK inhibitors to enhance antitumor immunity

Aberrant activation of oncogenic signaling pathways in tumors can promote resistance to the antitumor immune response. However, single blockade of these pathways is usually ineffective because of the complex crosstalk and feedback among oncogenic signaling pathways. The enhanced toxicity of free sma...

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Detalles Bibliográficos
Autores principales:	Yang, Qichao, Ma, Xianbin, Xiao, Yao, Zhang, Tian, Yang, Leilei, Yang, Shaochen, Liang, Mengyun, Wang, Shuo, Wu, Zhizhong, Xu, Zhigang, Sun, Zhijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293721/ https://www.ncbi.nlm.nih.gov/pubmed/35865097 http://dx.doi.org/10.1016/j.apsb.2022.02.024

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