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Characterizing unexpected interactions of a glutamine transporter inhibitor with members of the SLC1A transporter family
The solute carrier 1A family comprises a group of membrane proteins that act as dual-function amino acid transporters and chloride (Cl(−)) channels and includes the alanine serine cysteine transporters (ASCTs) as well as the excitatory amino acid transporters. ASCT2 is regarded as a promising target...
Autores principales: | Freidman, Natasha J., Briot, Chelsea, Ryan, Renae M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293768/ https://www.ncbi.nlm.nih.gov/pubmed/35752361 http://dx.doi.org/10.1016/j.jbc.2022.102178 |
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