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Identification of the amino acid residues involved in the species-dependent differences in the pyridoxine transport function of SLC19A3

Recent studies have shown that human solute carrier SLC19A3 (hSLC19A3) can transport pyridoxine (vitamin B6) in addition to thiamine (vitamin B1), its originally identified substrate, whereas rat and mouse orthologs of hSLC19A3 can transport thiamine but not pyridoxine. This finding implies that som...

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Detalles Bibliográficos
Autores principales: Miyake, Kohei, Yasujima, Tomoya, Takahashi, Syunsuke, Yamashiro, Takahiro, Yuasa, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293782/
https://www.ncbi.nlm.nih.gov/pubmed/35724964
http://dx.doi.org/10.1016/j.jbc.2022.102161

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