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Preoperative heart rate variability as a predictor of perioperative outcomes: a systematic review without meta-analysis

Heart rate variability (HRV) is a predictor of mortality and morbidity after non-lethal cardiac ischemia, but the relation between preoperatively measured HRV and intra- and postoperative complications is sparsely studied and most recently reviewed in 2007. We, therefore, reviewed the literature reg...

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Autores principales: Frandsen, Mikkel Nicklas, Mehlsen, Jesper, Foss, Nicolai Bang, Kehlet, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293802/
https://www.ncbi.nlm.nih.gov/pubmed/35092527
http://dx.doi.org/10.1007/s10877-022-00819-z
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author Frandsen, Mikkel Nicklas
Mehlsen, Jesper
Foss, Nicolai Bang
Kehlet, Henrik
author_facet Frandsen, Mikkel Nicklas
Mehlsen, Jesper
Foss, Nicolai Bang
Kehlet, Henrik
author_sort Frandsen, Mikkel Nicklas
collection PubMed
description Heart rate variability (HRV) is a predictor of mortality and morbidity after non-lethal cardiac ischemia, but the relation between preoperatively measured HRV and intra- and postoperative complications is sparsely studied and most recently reviewed in 2007. We, therefore, reviewed the literature regarding HRV as a predictor for intra- and postoperative complications and outcomes. We carried out a systematic review without meta-analysis. A PICO model was set up, and we searched PubMed, EMBASE, and CENTRAL. The screening was done by one author, but all authors performed detailed review of the included studies. We present data from studies on intraoperative and postoperative complications, which were too heterogeneous to warrant formal meta-analysis, and we provide a pragmatic review of HRV indices to facilitate understanding our findings. The review was registered in PROSPERO (CRD42021230641). We screened 2337 records for eligibility. 131 records went on to full-text assessment, 63 were included. In frequency analysis of HRV, low frequency to high frequency ratio could be a predictor for intraoperative hypotension in spinal anesthesia and lower total power could possibly predict intraoperative hypotension under general anesthesia. Detrended fluctuation analysis of HRV is a promising candidate for predicting postoperative atrial fibrillation. This updated review of the relation between preoperative HRV and surgical outcome suggests a clinically relevant role of HRV but calls for high quality studies due to methodological heterogeneity in the current literature. Areas for future research are suggested. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10877-022-00819-z.
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spelling pubmed-92938022022-07-20 Preoperative heart rate variability as a predictor of perioperative outcomes: a systematic review without meta-analysis Frandsen, Mikkel Nicklas Mehlsen, Jesper Foss, Nicolai Bang Kehlet, Henrik J Clin Monit Comput Review Paper Heart rate variability (HRV) is a predictor of mortality and morbidity after non-lethal cardiac ischemia, but the relation between preoperatively measured HRV and intra- and postoperative complications is sparsely studied and most recently reviewed in 2007. We, therefore, reviewed the literature regarding HRV as a predictor for intra- and postoperative complications and outcomes. We carried out a systematic review without meta-analysis. A PICO model was set up, and we searched PubMed, EMBASE, and CENTRAL. The screening was done by one author, but all authors performed detailed review of the included studies. We present data from studies on intraoperative and postoperative complications, which were too heterogeneous to warrant formal meta-analysis, and we provide a pragmatic review of HRV indices to facilitate understanding our findings. The review was registered in PROSPERO (CRD42021230641). We screened 2337 records for eligibility. 131 records went on to full-text assessment, 63 were included. In frequency analysis of HRV, low frequency to high frequency ratio could be a predictor for intraoperative hypotension in spinal anesthesia and lower total power could possibly predict intraoperative hypotension under general anesthesia. Detrended fluctuation analysis of HRV is a promising candidate for predicting postoperative atrial fibrillation. This updated review of the relation between preoperative HRV and surgical outcome suggests a clinically relevant role of HRV but calls for high quality studies due to methodological heterogeneity in the current literature. Areas for future research are suggested. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10877-022-00819-z. Springer Netherlands 2022-01-29 2022 /pmc/articles/PMC9293802/ /pubmed/35092527 http://dx.doi.org/10.1007/s10877-022-00819-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Paper
Frandsen, Mikkel Nicklas
Mehlsen, Jesper
Foss, Nicolai Bang
Kehlet, Henrik
Preoperative heart rate variability as a predictor of perioperative outcomes: a systematic review without meta-analysis
title Preoperative heart rate variability as a predictor of perioperative outcomes: a systematic review without meta-analysis
title_full Preoperative heart rate variability as a predictor of perioperative outcomes: a systematic review without meta-analysis
title_fullStr Preoperative heart rate variability as a predictor of perioperative outcomes: a systematic review without meta-analysis
title_full_unstemmed Preoperative heart rate variability as a predictor of perioperative outcomes: a systematic review without meta-analysis
title_short Preoperative heart rate variability as a predictor of perioperative outcomes: a systematic review without meta-analysis
title_sort preoperative heart rate variability as a predictor of perioperative outcomes: a systematic review without meta-analysis
topic Review Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293802/
https://www.ncbi.nlm.nih.gov/pubmed/35092527
http://dx.doi.org/10.1007/s10877-022-00819-z
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