Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden

Galectin-1 (Gal1) is a glycan-binding protein that promotes tumor progression by several distinct mechanisms. Through direct binding to vascular endothelial growth factor (VEGF)-receptor 2, Gal1 is able to induce VEGF-like signaling, which contributes to tumor angiogenesis. Furthermore, several stud...

Descripción completa

Detalles Bibliográficos
Autores principales: Femel, Julia, van Hooren, Luuk, Herre, Melanie, Cedervall, Jessica, Saupe, Falk, Huijbers, Elisabeth J. M., Verboogen, Danielle R. J., Reichel, Matthias, Thijssen, Victor L., Griffioen, Arjan W., Hellman, Lars, Dimberg, Anna, Olsson, Anna-Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293851/
https://www.ncbi.nlm.nih.gov/pubmed/35018481
http://dx.doi.org/10.1007/s00262-021-03139-4

Ejemplares similares

Ejemplares similares