Epigenomics of conventional type-I dendritic cells depicted preferential control of TLR9 versus TLR3 response by NCoR1 through differential IRF3 activation

Tight control of gene regulation in dendritic cells (DCs) is important to mount pathogen specific immune responses. Apart from transcription factor binding, dynamic regulation of enhancer activity through global transcriptional repressors like Nuclear Receptor Co-repressor 1 (NCoR1) plays a major ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Mishra, Gyan Prakash, Jha, Atimukta, Ahad, Abdul, Sen, Kaushik, Sen, Aishwarya, Podder, Sreeparna, Prusty, Subhasish, Biswas, Viplov Kumar, Gupta, Bhawna, Raghav, Sunil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293861/
https://www.ncbi.nlm.nih.gov/pubmed/35849243
http://dx.doi.org/10.1007/s00018-022-04424-w

Ejemplares similares

Ejemplares similares