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Local radiotherapy and E7 RNA-LPX vaccination show enhanced therapeutic efficacy in preclinical models of HPV16(+) cancer

Human papilloma virus (HPV) infection is a causative agent for several cancers types (genital, anal and head and neck region). The HPV E6 and E7 proteins are oncogenic drivers and thus are ideal candidates for therapeutic vaccination. We recently reported that a novel ribonucleic acid lipoplex (RNA-...

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Detalles Bibliográficos
Autores principales:	Salomon, Nadja, Selmi, Abderaouf, Grunwitz, Christian, Kong, Anthony, Stanganello, Eliana, Neumaier, Jennifer, Petschenka, Jutta, Diken, Mustafa, Kreiter, Sebastian, Türeci, Özlem, Sahin, Ugur, Vascotto, Fulvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293862/ https://www.ncbi.nlm.nih.gov/pubmed/34971406 http://dx.doi.org/10.1007/s00262-021-03134-9

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