N(6)-methyladenosine modification-mediated mRNA metabolism is essential for human pancreatic lineage specification and islet organogenesis

Pancreatic differentiation from human pluripotent stem cells (hPSCs) provides promising avenues for investigating development and treating diseases. N(6)-methyladenosine (m(6)A) is the most prevalent internal messenger RNA (mRNA) modification and plays pivotal roles in regulation of mRNA metabolism,...

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Detalles Bibliográficos
Autores principales: Ma, Xiaojie, Cao, Jie, Zhou, Ziyu, Lu, Yunkun, Li, Qin, Jin, Yan, Chen, Guo, Wang, Weiyun, Ge, Wenyan, Chen, Xi, Hu, Zhensheng, Shu, Xiao, Deng, Qian, Pu, Jiaqi, Liang, Chengzhen, Fu, Junfen, Liu, Jianzhao, Zhu, Saiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293889/
https://www.ncbi.nlm.nih.gov/pubmed/35851388
http://dx.doi.org/10.1038/s41467-022-31698-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293889/
https://www.ncbi.nlm.nih.gov/pubmed/35851388
http://dx.doi.org/10.1038/s41467-022-31698-2

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