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Control of blood glucose induced by meals for type-1 diabetics using an adaptive backstepping algorithm

In this study, an adaptive backstepping method is proposed to regulate the blood glucose induced by meals for type-1 diabetic patients. The backstepping controller is used to control the blood glucose level and an adaptive algorithm is utilized to compensate for the blood glucose induced by meals. M...

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Detalles Bibliográficos
Autores principales: Zahedifar, Rasoul, Keymasi Khalaji, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293929/
https://www.ncbi.nlm.nih.gov/pubmed/35851835
http://dx.doi.org/10.1038/s41598-022-16535-2
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author Zahedifar, Rasoul
Keymasi Khalaji, Ali
author_facet Zahedifar, Rasoul
Keymasi Khalaji, Ali
author_sort Zahedifar, Rasoul
collection PubMed
description In this study, an adaptive backstepping method is proposed to regulate the blood glucose induced by meals for type-1 diabetic patients. The backstepping controller is used to control the blood glucose level and an adaptive algorithm is utilized to compensate for the blood glucose induced by meals. Moreover, the effectiveness of the proposed method is evaluated by comparing results in two different case studies: in the presence of actuator faults and the loss of control input for a short while during treatment. Effects of unannounced meals three times a day are investigated for a nominal patient in every case. It is argued that adaptive backstepping is the preferred control method in either case. The Lyapunov theory is used to prove the stability of the proposed method. Obtained results, indicated that the adaptive backstepping controller is stable, and the desired level of glucose concentration is being tracked efficiently.
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spelling pubmed-92939292022-07-20 Control of blood glucose induced by meals for type-1 diabetics using an adaptive backstepping algorithm Zahedifar, Rasoul Keymasi Khalaji, Ali Sci Rep Article In this study, an adaptive backstepping method is proposed to regulate the blood glucose induced by meals for type-1 diabetic patients. The backstepping controller is used to control the blood glucose level and an adaptive algorithm is utilized to compensate for the blood glucose induced by meals. Moreover, the effectiveness of the proposed method is evaluated by comparing results in two different case studies: in the presence of actuator faults and the loss of control input for a short while during treatment. Effects of unannounced meals three times a day are investigated for a nominal patient in every case. It is argued that adaptive backstepping is the preferred control method in either case. The Lyapunov theory is used to prove the stability of the proposed method. Obtained results, indicated that the adaptive backstepping controller is stable, and the desired level of glucose concentration is being tracked efficiently. Nature Publishing Group UK 2022-07-18 /pmc/articles/PMC9293929/ /pubmed/35851835 http://dx.doi.org/10.1038/s41598-022-16535-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zahedifar, Rasoul
Keymasi Khalaji, Ali
Control of blood glucose induced by meals for type-1 diabetics using an adaptive backstepping algorithm
title Control of blood glucose induced by meals for type-1 diabetics using an adaptive backstepping algorithm
title_full Control of blood glucose induced by meals for type-1 diabetics using an adaptive backstepping algorithm
title_fullStr Control of blood glucose induced by meals for type-1 diabetics using an adaptive backstepping algorithm
title_full_unstemmed Control of blood glucose induced by meals for type-1 diabetics using an adaptive backstepping algorithm
title_short Control of blood glucose induced by meals for type-1 diabetics using an adaptive backstepping algorithm
title_sort control of blood glucose induced by meals for type-1 diabetics using an adaptive backstepping algorithm
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293929/
https://www.ncbi.nlm.nih.gov/pubmed/35851835
http://dx.doi.org/10.1038/s41598-022-16535-2
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