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Anaphylaxis in older adult patients: a 10-year retrospective experience()

BACKGROUND: Despite the worldwide increase in life expectancy and the elderly population, very little is known about the characteristics of anaphylaxis in older adults. METHODS: A retrospective scan was made of the files of patients who presented at the Allergy Unit of our clinic between October 201...

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Autores principales: Yıldız, Eray, Arslan, Şevket, Çölkesen, Fatih, Evcen, Recep, Sadi Aykan, Filiz, Kılınç, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293944/
https://www.ncbi.nlm.nih.gov/pubmed/35891674
http://dx.doi.org/10.1016/j.waojou.2022.100665
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author Yıldız, Eray
Arslan, Şevket
Çölkesen, Fatih
Evcen, Recep
Sadi Aykan, Filiz
Kılınç, Mehmet
author_facet Yıldız, Eray
Arslan, Şevket
Çölkesen, Fatih
Evcen, Recep
Sadi Aykan, Filiz
Kılınç, Mehmet
author_sort Yıldız, Eray
collection PubMed
description BACKGROUND: Despite the worldwide increase in life expectancy and the elderly population, very little is known about the characteristics of anaphylaxis in older adults. METHODS: A retrospective scan was made of the files of patients who presented at the Allergy Unit of our clinic between October 2011 and October 2021. The study included 971 patients aged ≥18 years who met the criteria for diagnosis of anaphylaxis. The patients were separated into 2 groups of adults (18–64 years) and older adults (≥65 years). RESULTS: The adult group included 887 (91.3%) patients and the older adult group, 84 (8.7%) patients. Comorbid diseases were seen more frequently in the older adults than in the adult group (p < 0.001). Drugs were seen to be the most common trigger of anaphylaxis in both groups, and this was more common in the older adult group (p = 0.039). Food was a more common trigger of anaphylaxis in the adult group than in the older adult group (p = 0.017). In both groups, the skin was the organ most affected, and was less affected in the older adults than in the adults (p = 0.020). Cardiovascular symptoms were seen significantly more and respiratory symptoms significantly less in the older adult group (p < 0.001, p = 0.002, respectively). Admission to the hospital and the intensive care unit was more frequent in the older adult group and rates of adrenalin administration were higher compared to the adult group (p < 0.001 for all). CONCLUSION: Anaphylaxis in the older adults is generally caused by drugs. Older adults were found to have more cardiovascular symptoms and more frequent adrenalin injections, hospitalizations and intensive care unit admissions.
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spelling pubmed-92939442022-07-25 Anaphylaxis in older adult patients: a 10-year retrospective experience() Yıldız, Eray Arslan, Şevket Çölkesen, Fatih Evcen, Recep Sadi Aykan, Filiz Kılınç, Mehmet World Allergy Organ J Full-Length Article BACKGROUND: Despite the worldwide increase in life expectancy and the elderly population, very little is known about the characteristics of anaphylaxis in older adults. METHODS: A retrospective scan was made of the files of patients who presented at the Allergy Unit of our clinic between October 2011 and October 2021. The study included 971 patients aged ≥18 years who met the criteria for diagnosis of anaphylaxis. The patients were separated into 2 groups of adults (18–64 years) and older adults (≥65 years). RESULTS: The adult group included 887 (91.3%) patients and the older adult group, 84 (8.7%) patients. Comorbid diseases were seen more frequently in the older adults than in the adult group (p < 0.001). Drugs were seen to be the most common trigger of anaphylaxis in both groups, and this was more common in the older adult group (p = 0.039). Food was a more common trigger of anaphylaxis in the adult group than in the older adult group (p = 0.017). In both groups, the skin was the organ most affected, and was less affected in the older adults than in the adults (p = 0.020). Cardiovascular symptoms were seen significantly more and respiratory symptoms significantly less in the older adult group (p < 0.001, p = 0.002, respectively). Admission to the hospital and the intensive care unit was more frequent in the older adult group and rates of adrenalin administration were higher compared to the adult group (p < 0.001 for all). CONCLUSION: Anaphylaxis in the older adults is generally caused by drugs. Older adults were found to have more cardiovascular symptoms and more frequent adrenalin injections, hospitalizations and intensive care unit admissions. World Allergy Organization 2022-07-14 /pmc/articles/PMC9293944/ /pubmed/35891674 http://dx.doi.org/10.1016/j.waojou.2022.100665 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Full-Length Article
Yıldız, Eray
Arslan, Şevket
Çölkesen, Fatih
Evcen, Recep
Sadi Aykan, Filiz
Kılınç, Mehmet
Anaphylaxis in older adult patients: a 10-year retrospective experience()
title Anaphylaxis in older adult patients: a 10-year retrospective experience()
title_full Anaphylaxis in older adult patients: a 10-year retrospective experience()
title_fullStr Anaphylaxis in older adult patients: a 10-year retrospective experience()
title_full_unstemmed Anaphylaxis in older adult patients: a 10-year retrospective experience()
title_short Anaphylaxis in older adult patients: a 10-year retrospective experience()
title_sort anaphylaxis in older adult patients: a 10-year retrospective experience()
topic Full-Length Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293944/
https://www.ncbi.nlm.nih.gov/pubmed/35891674
http://dx.doi.org/10.1016/j.waojou.2022.100665
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