Monocytic myeloid-derived suppressive cells mitigate over-adipogenesis of bone marrow microenvironment in aplastic anemia by inhibiting CD8(+) T cells

Aplastic anemia (AA) is a blood disorder resulted from over-activated T-cell related hematopoietic failure, with the characterization of hypocellularity and enhanced adipogenic differentiation of mesenchymal stroma cells (MSCs) in bone marrow (BM). However, little is known about the relationship bet...

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Detalles Bibliográficos
Autores principales: Qu, Ying, Sun, Zhengxu, Yuan, Yan, Li, Zifeng, Wang, Fen, Wu, Kunpeng, Yu, Huihui, Lin, Qiwang, Fei, He, Chen, Jian, Qian, Maoxiang, Cheng, Yunfeng, Jiang, Hua, Chen, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293984/
https://www.ncbi.nlm.nih.gov/pubmed/35851002
http://dx.doi.org/10.1038/s41419-022-05080-5

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