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An immunological autobiography: my year as a COVID-19 vaccine trial participant
After enrolling in the Moderna phase III clinical trial, I collected my own biological samples pre- and post-immunization in the event of being a recipient of the experimental vaccine. The evidence strongly supports the conclusion that I did not receive the placebo. The analysis is admittedly limite...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293989/ https://www.ncbi.nlm.nih.gov/pubmed/35851389 http://dx.doi.org/10.1038/s41541-022-00502-z |
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author | Kedl, Ross M. |
author_facet | Kedl, Ross M. |
author_sort | Kedl, Ross M. |
collection | PubMed |
description | After enrolling in the Moderna phase III clinical trial, I collected my own biological samples pre- and post-immunization in the event of being a recipient of the experimental vaccine. The evidence strongly supports the conclusion that I did not receive the placebo. The analysis is admittedly limited to an n of 1, but the results fit well with data taken from published works and represent one of the more comprehensive longitudinal evaluations of vaccine-elicited immunity within a single individual yet to be undertaken. Though the data amount to a well-documented anecdote, given its granularity, it is not without its insights and may be of further use in directing future longitudinal studies that have actual statistical significance. |
format | Online Article Text |
id | pubmed-9293989 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-92939892022-07-19 An immunological autobiography: my year as a COVID-19 vaccine trial participant Kedl, Ross M. NPJ Vaccines Comment After enrolling in the Moderna phase III clinical trial, I collected my own biological samples pre- and post-immunization in the event of being a recipient of the experimental vaccine. The evidence strongly supports the conclusion that I did not receive the placebo. The analysis is admittedly limited to an n of 1, but the results fit well with data taken from published works and represent one of the more comprehensive longitudinal evaluations of vaccine-elicited immunity within a single individual yet to be undertaken. Though the data amount to a well-documented anecdote, given its granularity, it is not without its insights and may be of further use in directing future longitudinal studies that have actual statistical significance. Nature Publishing Group UK 2022-07-18 /pmc/articles/PMC9293989/ /pubmed/35851389 http://dx.doi.org/10.1038/s41541-022-00502-z Text en © The Author(s) 2022, corrected publication 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Comment Kedl, Ross M. An immunological autobiography: my year as a COVID-19 vaccine trial participant |
title | An immunological autobiography: my year as a COVID-19 vaccine trial participant |
title_full | An immunological autobiography: my year as a COVID-19 vaccine trial participant |
title_fullStr | An immunological autobiography: my year as a COVID-19 vaccine trial participant |
title_full_unstemmed | An immunological autobiography: my year as a COVID-19 vaccine trial participant |
title_short | An immunological autobiography: my year as a COVID-19 vaccine trial participant |
title_sort | immunological autobiography: my year as a covid-19 vaccine trial participant |
topic | Comment |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293989/ https://www.ncbi.nlm.nih.gov/pubmed/35851389 http://dx.doi.org/10.1038/s41541-022-00502-z |
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