Case Report: Reversible Hyperglycemia Following Rapamycin Treatment for Atypical Choroid Plexus Papilloma in an Infant

In this study, atypical choroid plexus papilloma was treated with high-dose rapamycin for 17 days preoperatively in an infant. Rapamycin significantly reduced the blood supply to the tumor while reducing the tumor volume, and most of the tumor was resected successfully. However, the infant developed...

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Detalles Bibliográficos
Autores principales: Liu, Jiale, Luo, Minjie, Lv, Siyuan, Tao, Shaohua, Wu, Zhu, Yu, Lihua, Lin, Danna, Huang, Lulu, Wu, Li, Liao, Xu, Zi, Juan, Lai, Xiaorong, Yuan, Yuting, Zhang, Wangming, Yang, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294177/
https://www.ncbi.nlm.nih.gov/pubmed/35865311
http://dx.doi.org/10.3389/fendo.2022.865913
Descripción
Sumario:In this study, atypical choroid plexus papilloma was treated with high-dose rapamycin for 17 days preoperatively in an infant. Rapamycin significantly reduced the blood supply to the tumor while reducing the tumor volume, and most of the tumor was resected successfully. However, the infant developed hyperglycemia related to the rapamycin dose, which was effectively controlled by adjusting the dose and applying insulin.

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