Case Report: Reversible Hyperglycemia Following Rapamycin Treatment for Atypical Choroid Plexus Papilloma in an Infant

In this study, atypical choroid plexus papilloma was treated with high-dose rapamycin for 17 days preoperatively in an infant. Rapamycin significantly reduced the blood supply to the tumor while reducing the tumor volume, and most of the tumor was resected successfully. However, the infant developed...

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Autores principales: Liu, Jiale, Luo, Minjie, Lv, Siyuan, Tao, Shaohua, Wu, Zhu, Yu, Lihua, Lin, Danna, Huang, Lulu, Wu, Li, Liao, Xu, Zi, Juan, Lai, Xiaorong, Yuan, Yuting, Zhang, Wangming, Yang, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294177/
https://www.ncbi.nlm.nih.gov/pubmed/35865311
http://dx.doi.org/10.3389/fendo.2022.865913
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author Liu, Jiale
Luo, Minjie
Lv, Siyuan
Tao, Shaohua
Wu, Zhu
Yu, Lihua
Lin, Danna
Huang, Lulu
Wu, Li
Liao, Xu
Zi, Juan
Lai, Xiaorong
Yuan, Yuting
Zhang, Wangming
Yang, Lihua
author_facet Liu, Jiale
Luo, Minjie
Lv, Siyuan
Tao, Shaohua
Wu, Zhu
Yu, Lihua
Lin, Danna
Huang, Lulu
Wu, Li
Liao, Xu
Zi, Juan
Lai, Xiaorong
Yuan, Yuting
Zhang, Wangming
Yang, Lihua
author_sort Liu, Jiale
collection PubMed
description In this study, atypical choroid plexus papilloma was treated with high-dose rapamycin for 17 days preoperatively in an infant. Rapamycin significantly reduced the blood supply to the tumor while reducing the tumor volume, and most of the tumor was resected successfully. However, the infant developed hyperglycemia related to the rapamycin dose, which was effectively controlled by adjusting the dose and applying insulin.
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spelling pubmed-92941772022-07-20 Case Report: Reversible Hyperglycemia Following Rapamycin Treatment for Atypical Choroid Plexus Papilloma in an Infant Liu, Jiale Luo, Minjie Lv, Siyuan Tao, Shaohua Wu, Zhu Yu, Lihua Lin, Danna Huang, Lulu Wu, Li Liao, Xu Zi, Juan Lai, Xiaorong Yuan, Yuting Zhang, Wangming Yang, Lihua Front Endocrinol (Lausanne) Endocrinology In this study, atypical choroid plexus papilloma was treated with high-dose rapamycin for 17 days preoperatively in an infant. Rapamycin significantly reduced the blood supply to the tumor while reducing the tumor volume, and most of the tumor was resected successfully. However, the infant developed hyperglycemia related to the rapamycin dose, which was effectively controlled by adjusting the dose and applying insulin. Frontiers Media S.A. 2022-07-05 /pmc/articles/PMC9294177/ /pubmed/35865311 http://dx.doi.org/10.3389/fendo.2022.865913 Text en Copyright © 2022 Liu, Luo, Lv, Tao, Wu, Yu, Lin, Huang, Wu, Liao, Zi, Lai, Yuan, Zhang and Yang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Liu, Jiale
Luo, Minjie
Lv, Siyuan
Tao, Shaohua
Wu, Zhu
Yu, Lihua
Lin, Danna
Huang, Lulu
Wu, Li
Liao, Xu
Zi, Juan
Lai, Xiaorong
Yuan, Yuting
Zhang, Wangming
Yang, Lihua
Case Report: Reversible Hyperglycemia Following Rapamycin Treatment for Atypical Choroid Plexus Papilloma in an Infant
title Case Report: Reversible Hyperglycemia Following Rapamycin Treatment for Atypical Choroid Plexus Papilloma in an Infant
title_full Case Report: Reversible Hyperglycemia Following Rapamycin Treatment for Atypical Choroid Plexus Papilloma in an Infant
title_fullStr Case Report: Reversible Hyperglycemia Following Rapamycin Treatment for Atypical Choroid Plexus Papilloma in an Infant
title_full_unstemmed Case Report: Reversible Hyperglycemia Following Rapamycin Treatment for Atypical Choroid Plexus Papilloma in an Infant
title_short Case Report: Reversible Hyperglycemia Following Rapamycin Treatment for Atypical Choroid Plexus Papilloma in an Infant
title_sort case report: reversible hyperglycemia following rapamycin treatment for atypical choroid plexus papilloma in an infant
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294177/
https://www.ncbi.nlm.nih.gov/pubmed/35865311
http://dx.doi.org/10.3389/fendo.2022.865913
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