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Allergen-Specific IgA Antibodies Block IgE-Mediated Activation of Mast Cells and Basophils

Mast cells and basophils have long been implicated in the pathogenesis of IgE-mediated hypersensitivity reactions. They express the high-affinity IgE receptor, FcϵRI, on their surface. Antigen-induced crosslinking of IgE antibodies bound to that receptor triggers a signaling cascade that results in...

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Detalles Bibliográficos
Autores principales:	El Ansari, Yasmeen S., Kanagaratham, Cynthia, Burton, Oliver T., Santos, Jenna V., Hollister, Brianna-Marie A., Lewis, Owen L., Renz, Harald, Oettgen, Hans C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294179/ https://www.ncbi.nlm.nih.gov/pubmed/35865546 http://dx.doi.org/10.3389/fimmu.2022.881655

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