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Toxicity and toxicokinetic assessment of an anti-tubercular drug pretomanid in cynomolgus monkeys
Pretomanid is a nitroimidazooxazine antimycobacterial drug that was approved in more than 10 countries as part of a three-drug, all oral regimen, consisting of bedaquiline, pretomanid, and linezolid (BPaL) for 6-months treatment of adults with pulmonary extensively drug-resistant tuberculosis (XDR-T...
Autores principales: | Bruning-Barry, Rebecca, Ambroso, Jeffrey L., Dillberger, John, Yang, Tian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294187/ https://www.ncbi.nlm.nih.gov/pubmed/35864921 http://dx.doi.org/10.1016/j.toxrep.2022.04.021 |
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