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Ontogeny of cellular organization and LGR5 expression in porcine cochlea revealed using tissue clearing and 3D imaging

Over 11% of the world’s population experience hearing loss. Although there are promising studies to restore hearing in rodent models, the size, ontogeny, genetics, and frequency range of hearing of most rodents’ cochlea do not match that of humans. The porcine cochlea can bridge this gap as it share...

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Detalles Bibliográficos
Autores principales: Moatti, Adele, Li, Chen, Sivadanam, Sasank, Cai, Yuheng, Ranta, James, Piedrahita, Jorge A., Cheng, Alan G., Ligler, Frances S., Greenbaum, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294204/
https://www.ncbi.nlm.nih.gov/pubmed/35865132
http://dx.doi.org/10.1016/j.isci.2022.104695