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Inhibition of Notch Signaling Stimulates Osteoclastogenesis From the Common Trilineage Progenitor Under Inflammatory Conditions

Osteoclasts, macrophages and dendritic cells (DCs) can be derived from a common trilineage myeloid progenitor of hematopoietic origin. Progenitor commitment is susceptible to regulation through Notch signaling. Our aim was to determine the effects of Notch modulation on trilineage progenitor commitm...

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Detalles Bibliográficos
Autores principales: Filipović, Maša, Flegar, Darja, Šućur, Alan, Šisl, Dino, Kavazović, Inga, Antica, Mariastefania, Kelava, Tomislav, Kovačić, Nataša, Grčević, Danka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294223/
https://www.ncbi.nlm.nih.gov/pubmed/35865541
http://dx.doi.org/10.3389/fimmu.2022.902947