Cargando…
Inhibition of Notch Signaling Stimulates Osteoclastogenesis From the Common Trilineage Progenitor Under Inflammatory Conditions
Osteoclasts, macrophages and dendritic cells (DCs) can be derived from a common trilineage myeloid progenitor of hematopoietic origin. Progenitor commitment is susceptible to regulation through Notch signaling. Our aim was to determine the effects of Notch modulation on trilineage progenitor commitm...
Autores principales: | Filipović, Maša, Flegar, Darja, Šućur, Alan, Šisl, Dino, Kavazović, Inga, Antica, Mariastefania, Kelava, Tomislav, Kovačić, Nataša, Grčević, Danka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294223/ https://www.ncbi.nlm.nih.gov/pubmed/35865541 http://dx.doi.org/10.3389/fimmu.2022.902947 |
Ejemplares similares
-
Transcriptome profiling of osteoclast subsets associated with arthritis: A pathogenic role of CCR2(hi) osteoclast progenitors
por: Filipović, Maša, et al.
Publicado: (2022) -
Tamoxifen Ameliorates Cholestatic Liver Fibrosis in Mice: Upregulation of TGFβ and IL6 Is a Potential Protective Mechanism
por: Šisl, Dino, et al.
Publicado: (2022) -
Preventive CCL2/CCR2 Axis Blockade Suppresses Osteoclast Activity in a Mouse Model of Rheumatoid Arthritis by Reducing Homing of CCR2(hi) Osteoclast Progenitors to the Affected Bone
por: Flegar, Darja, et al.
Publicado: (2021) -
FasL (rs763110) gene polymorphism is not associated with susceptibility to rheumatoid arthritis in Croatian population
por: Artuković, Marinko, et al.
Publicado: (2020) -
Chemokine signals are crucial for enhanced homing and differentiation of circulating osteoclast progenitor cells
por: Sucur, Alan, et al.
Publicado: (2017)