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MiR-208b/miR-21 Promotes the Progression of Cardiac Fibrosis Through the Activation of the TGF-β1/Smad-3 Signaling Pathway: An in vitro and in vivo Study

BACKGROUND: Regulatory molecule microRNAs (miRNAs) have been implicated in myocardial fibrosis. However, the specific mechanism by which they lead to myocardial fibrosis remains unclear. This study aimed to explore the roles of miR-208b, miR-21 and transforming growth factor-β1 (TGF-β1)/Smad-3 signa...

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Detalles Bibliográficos
Autores principales:	Zhang, Yifan, Yuan, Bo, Xu, Yue, Zhou, Na, Zhang, Ruiqi, Lu, Lan, Feng, Zhanbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294285/ https://www.ncbi.nlm.nih.gov/pubmed/35865391 http://dx.doi.org/10.3389/fcvm.2022.924629

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