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A naturally occurring membrane-anchored Gα(s) variant, XLα(s), activates phospholipase Cβ4

Extra-large stimulatory Gα (XLα(s)) is a large variant of G protein α(s) subunit (Gα(s)) that uses an alternative promoter and thus differs from Gα(s) at the first exon. XLα(s) activation by G protein–coupled receptors mediates cAMP generation, similarly to Gα(s); however, Gα(s) and XLα(s) have been...

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Detalles Bibliográficos
Autores principales: Phan, Hoa T.N., Loomis, Joseph, Abraham, Saji, He, Qing, Bastepe, Murat, Smrcka, Alan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294334/
https://www.ncbi.nlm.nih.gov/pubmed/35709985
http://dx.doi.org/10.1016/j.jbc.2022.102134

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