Optimizing CRISPR/Cas9 Editing of Repetitive Single Nucleotide Variants

CRISPR/Cas9, base editors and prime editors comprise the contemporary genome editing toolbox. Many studies have optimized the use of CRISPR/Cas9, as the original CRISPR genome editing system, in substituting single nucleotides by homology directed repair (HDR), although this remains challenging. Stu...

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Detalles Bibliográficos
Autores principales: Usher, Inga, Ligammari, Lorena, Ahrabi, Sara, Hepburn, Emily, Connolly, Calum, Bond, Gareth L., Flanagan, Adrienne M., Cottone, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genome Editing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294353/
https://www.ncbi.nlm.nih.gov/pubmed/35865001
http://dx.doi.org/10.3389/fgeed.2022.932434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294353/
https://www.ncbi.nlm.nih.gov/pubmed/35865001
http://dx.doi.org/10.3389/fgeed.2022.932434

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