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Comprehensive Assessment of Indian Variations in the Druggable Kinome Landscape Highlights Distinct Insights at the Sequence, Structure and Pharmacogenomic Stratum

India confines more than 17% of the world’s population and has a diverse genetic makeup with several clinically relevant rare mutations belonging to many sub-group which are undervalued in global sequencing datasets like the 1000 Genome data (1KG) containing limited samples for Indian ethnicity. Suc...

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Detalles Bibliográficos
Autores principales: Panda, Gayatri, Mishra, Neha, Sharma, Disha, Kutum, Rintu, Bhoyar, Rahul C., Jain, Abhinav, Imran, Mohamed, Senthilvel, Vigneshwar, Divakar, Mohit Kumar, Mishra, Anushree, Garg, Parth, Banerjee, Priyanka, Sivasubbu, Sridhar, Scaria, Vinod, Ray, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294532/
https://www.ncbi.nlm.nih.gov/pubmed/35865963
http://dx.doi.org/10.3389/fphar.2022.858345