Miltefosine and Benznidazole Combination Improve Anti-Trypanosoma cruzi In Vitro and In Vivo Efficacy

Drug repurposing and combination therapy have been proposed as cost-effective strategies to improve Chagas disease treatment. Miltefosine (MLT), a synthetic alkylphospholipid initially developed for breast cancer and repositioned for leishmaniasis, is a promising candidate against Trypanosoma cruzi...

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Detalles Bibliográficos
Autores principales: Gulin, Julián Ernesto Nicolás, Bisio, Margarita María Catalina, Rocco, Daniela, Altcheh, Jaime, Solana, María Elisa, García-Bournissen, Facundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294734/
https://www.ncbi.nlm.nih.gov/pubmed/35865815
http://dx.doi.org/10.3389/fcimb.2022.855119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294734/
https://www.ncbi.nlm.nih.gov/pubmed/35865815
http://dx.doi.org/10.3389/fcimb.2022.855119

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